Identified secondary metabolite clusters

Cluster Type From To
The following clusters are from record KL198004.1:
Cluster 1Terpene16689181690215
The following clusters are from record KL198005.1:
Cluster 2Terpene595319616512
Cluster 3Other14008681443705
The following clusters are from record KL198006.1:
Cluster 4Other28417832885032
The following clusters are from record KL198007.1:
Cluster 5Terpene29993613026326
The following clusters are from record KL198008.1:
Cluster 6Other261856306047
Cluster 7Terpene34806843501857
The following clusters are from record KL198009.1:
Cluster 8Terpene185771207422
The following clusters are from record KL198010.1:
Cluster 9Terpene377343402534
Cluster 10Other432075475696
Cluster 11Terpene13522201373490
Cluster 12Terpene17538471775063
Cluster 13Terpene18742171895482
The following clusters are from record KL198011.1:
Cluster 14T1fas547192600068
Cluster 15Siderophore9853951001169
Cluster 16Terpene10268081047986
Cluster 17Terpene12526451273897
Cluster 18T1pks19993502045559
Cluster 19Terpene20387172059878
The following clusters are from record KL198012.1:
Cluster 20Ubia_cyclase203851244666
Cluster 21Other12723301324528
Cluster 22Other14628541507027
Cluster 23Terpene17440811766402
The following clusters are from record KL198013.1:
Cluster 24Other767508811785
The following clusters are from record KL198014.1:
Cluster 25Nrps9988141046727
Cluster 26Other10372141081783
Cluster 27Ubia_cyclase17145471755649

Cluster 1 - Terpene

Gene cluster description

Gene Cluster 1. Type = terpene. Location: 1668918 - 1690215 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 2 - Terpene

Gene cluster description

Gene Cluster 2. Type = terpene. Location: 595319 - 616512 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 3 - Other

Gene cluster description

Gene Cluster 3. Type = other. Location: 1400868 - 1443705 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 4 - Other

Gene cluster description

Gene Cluster 4. Type = other. Location: 2841783 - 2885032 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 5 - Terpene

Gene cluster description

Gene Cluster 5. Type = terpene. Location: 2999361 - 3026326 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 6 - Other

Gene cluster description

Gene Cluster 6. Type = other. Location: 261856 - 306047 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 7 - Terpene

Gene cluster description

Gene Cluster 7. Type = terpene. Location: 3480684 - 3501857 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 8 - Terpene

Gene cluster description

Gene Cluster 8. Type = terpene. Location: 185771 - 207422 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 9 - Terpene

Gene cluster description

Gene Cluster 9. Type = terpene. Location: 377343 - 402534 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 10 - Other

Gene cluster description

Gene Cluster 10. Type = other. Location: 432075 - 475696 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 11 - Terpene

Gene cluster description

Gene Cluster 11. Type = terpene. Location: 1352220 - 1373490 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 12 - Terpene

Gene cluster description

Gene Cluster 12. Type = terpene. Location: 1753847 - 1775063 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 13 - Terpene

Gene cluster description

Gene Cluster 13. Type = terpene. Location: 1874217 - 1895482 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 14 - T1fas

Gene cluster description

Gene Cluster 14. Type = t1fas. Location: 547192 - 600068 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 15 - Siderophore

Gene cluster description

Gene Cluster 15. Type = siderophore. Location: 985395 - 1001169 nt. Click on genes for more information.
Show pHMM detection rules used
siderophore: (IucA_IucC)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 16 - Terpene

Gene cluster description

Gene Cluster 16. Type = terpene. Location: 1026808 - 1047986 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 17 - Terpene

Gene cluster description

Gene Cluster 17. Type = terpene. Location: 1252645 - 1273897 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 18 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-mal)
PLEOSDRAFT_1047319
PKS signature: N/A
Minowa: trans-1,2-CPDA
consensus: pk

PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 18. Type = t1pks. Location: 1999350 - 2045559 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 19 - Terpene

Gene cluster description

Gene Cluster 19. Type = terpene. Location: 2038717 - 2059878 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 20 - Ubia_cyclase

Gene cluster description

Gene Cluster 20. Type = UbiA_cyclase. Location: 203851 - 244666 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 21 - Other

Gene cluster description

Gene Cluster 21. Type = other. Location: 1272330 - 1324528 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 22 - Other

Gene cluster description

Gene Cluster 22. Type = other. Location: 1462854 - 1507027 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 23 - Terpene

Gene cluster description

Gene Cluster 23. Type = terpene. Location: 1744081 - 1766402 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 24 - Other

Gene cluster description

Gene Cluster 24. Type = other. Location: 767508 - 811785 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 25 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(ala)
PLEOSDRAFT_1051206
NRPSPredictor2 SVM: ala
Stachelhaus code: lys
Minowa: ala
consensus: ala

Database cross-links

Gene cluster description

Gene Cluster 25. Type = nrps. Location: 998814 - 1046727 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 26 - Other

Gene cluster description

Gene Cluster 26. Type = other. Location: 1037214 - 1081783 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 27 - Ubia_cyclase

Gene cluster description

Gene Cluster 27. Type = UbiA_cyclase. Location: 1714547 - 1755649 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters