Identified secondary metabolite clusters

Cluster Type From To
The following clusters are from record KB908481.1:
Cluster 1Nrps-t1fas42373114884
Cluster 2T3pks573506614989
Cluster 3Nrps13860651445397
Cluster 4T1pks14381561492667
Cluster 5Other25707492615470
The following clusters are from record KB908482.1:
Cluster 6Other10217641065397
Cluster 7Terpene16741881695328
Cluster 8T1pks16984691746126
Cluster 9Nrps19082911973251
The following clusters are from record KB908493.1:
Cluster 10T1pks377371424288
The following clusters are from record KB908504.1:
Cluster 11Nrps472758523312
Cluster 12T1pks547304593884
The following clusters are from record KB908526.1:
Cluster 13Lantipeptide1210149053
Cluster 14T1pks408942454480
Cluster 15Nrps583410632100
The following clusters are from record KB908570.1:
Cluster 16T1pks234127282387
The following clusters are from record KB908592.1:
Cluster 17Terpene25328392554238
Cluster 18Nrps-t1pks35254903581557
The following clusters are from record KB908593.1:
Cluster 19T1pks395948444697
Cluster 20Nrps-t1pks492645545253
The following clusters are from record KB908604.1:
Cluster 21Other564141607482
The following clusters are from record KB908615.1:
Cluster 22T1pks405520524673
The following clusters are from record KB908648.1:
Cluster 23Terpene130258151652
The following clusters are from record KB908692.1:
Cluster 24T1pks137122
Cluster 25T1pks57574105744
The following clusters are from record KB908703.1:
Cluster 26Nrps395602457804
Cluster 27T1pks16681111716182
Cluster 28T1pks30809773129360
Cluster 29T1pks34324513479694
The following clusters are from record KB908814.1:
Cluster 30T1pks-nrps306299358493
Cluster 31Terpene17693661790712
Cluster 32T1pks23579432405329
The following clusters are from record KB908833.1:
Cluster 33Other457824500958
Cluster 34T1pks15201101568361
Cluster 35T2fas18164031858032
The following clusters are from record KB908844.1:
Cluster 36T1pks5051298088
Cluster 37T1fas18090731854767
Cluster 38Nrps20570322113337
Cluster 39T1pks22234602267361
The following clusters are from record KB908855.1:
Cluster 40Other461091504939
Cluster 41T1pks13821781429965
Cluster 42Nrps18993481944485
The following clusters are from record KB908866.1:
Cluster 43Terpene1275935614
Cluster 44Terpene597965619594
Cluster 45Other9873191030673
Cluster 46T1fas-nrps16221481689532
The following clusters are from record KB908877.1:
Cluster 47T1pks142363189917
Cluster 48Other13020321345265
Cluster 49T1pks16883921737224
Cluster 50T1pks18055191854360

Cluster 1 - Nrps-t1fas

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pro-ala-ala-nrp)
SETTUDRAFT_29755
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: pro
Minowa: pro
consensus: pro

NRPSPredictor2 SVM: ala
Stachelhaus code: ala
Minowa: ala
consensus: ala

NRPSPredictor2 SVM: ala
Stachelhaus code: ala
Minowa: ala
consensus: ala

NRPSPredictor2 SVM: ala
Stachelhaus code: N/A
Minowa: aeo
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 1. Type = nrps-t1fas. Location: 42373 - 114884 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 2 - T3pks

Gene cluster description

Gene Cluster 2. Type = t3pks. Location: 573506 - 614989 nt. Click on genes for more information.
Show pHMM detection rules used
t3pks: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 3 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp) + (nrp)
SETTUDRAFT_30097
NRPSPredictor2 SVM: N/A
Stachelhaus code: N/A
Minowa: glu
consensus: nrp

SETTUDRAFT_85461
NRPSPredictor2 SVM: hydrophobic-aromatic
Stachelhaus code: gly
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 3. Type = nrps. Location: 1386065 - 1445397 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 4 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk) + (mal)
SETTUDRAFT_152662
PKS signature: mal
Minowa: mal
consensus: mal

SETTUDRAFT_30113
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 4. Type = t1pks. Location: 1438156 - 1492667 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 5 - Other

Gene cluster description

Gene Cluster 5. Type = other. Location: 2570749 - 2615470 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 6 - Other

Gene cluster description

Gene Cluster 6. Type = other. Location: 1021764 - 1065397 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 7 - Terpene

Gene cluster description

Gene Cluster 7. Type = terpene. Location: 1674188 - 1695328 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 8 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_158567
PKS signature: N/A
Minowa: mxmal
consensus: pk

Gene cluster description

Gene Cluster 8. Type = t1pks. Location: 1698469 - 1746126 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 9 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp) + (leu)
SETTUDRAFT_36641
NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: leu
Minowa: leu
consensus: leu

SETTUDRAFT_51661
NRPSPredictor2 SVM: N/A
Stachelhaus code: gly
Minowa: aeo
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 9. Type = nrps. Location: 1908291 - 1973251 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 10 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_103204
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 10. Type = t1pks. Location: 377371 - 424288 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 11 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp)
SETTUDRAFT_104817
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: N/A
Minowa: gln
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 11. Type = nrps. Location: 472758 - 523312 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 12 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
SETTUDRAFT_175651
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 12. Type = t1pks. Location: 547304 - 593884 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 13 - Lantipeptide

Gene cluster description

Gene Cluster 13. Type = lantipeptide. Location: 12101 - 49053 nt. Click on genes for more information.
Show pHMM detection rules used
lantipeptide: ((Lant_dehyd_N & Lant_dehyd_C) or cluster(LANC_like,Flavoprotein) or cluster(LANC_like,Trp_halogenase) or cluster(LANC_like,p450) or (LANC_like & Pkinase) or (LANC_like & DUF4135) or cluster(LANC_like,Lant_dehyd_N) or cluster(LANC_like,Lant_dehyd_C) or cluster(LANC_like,adh_short) or cluster(LANC_like,adh_short_C2) or TIGR03731 or Antimicr18 or Gallidermin or L_biotic_A or TIGR03731 or leader_d or leader_eh or leader_abc or mature_d or mature_ab or mature_a or mature_b or mature_ha or mature_h_beta or lacticin_l or lacticin_mat or LD_lanti_pre or strep_PEQAXS)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

No core peptides found.

Homologous gene clusters

Cluster 14 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
SETTUDRAFT_38126
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 14. Type = t1pks. Location: 408942 - 454480 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 15 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp-nrp)
SETTUDRAFT_54477
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: tyr
Minowa: bmt
consensus: nrp

NRPSPredictor2 SVM: leu
Stachelhaus code: N/A
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 15. Type = nrps. Location: 583410 - 632100 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 16 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_184365
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 16. Type = t1pks. Location: 234127 - 282387 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 17 - Terpene

Gene cluster description

Gene Cluster 17. Type = terpene. Location: 2532839 - 2554238 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 18 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-leu)
SETTUDRAFT_179218
PKS signature: mal
Minowa: mmal
consensus: pk

NRPSPredictor2 SVM: leu
Stachelhaus code: leu
Minowa: lys
consensus: leu

Database cross-links

Gene cluster description

Gene Cluster 18. Type = nrps-t1pks. Location: 3525490 - 3581557 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 19 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_39554
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 19. Type = t1pks. Location: 395948 - 444697 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 20 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-nrp)
SETTUDRAFT_47468
PKS signature: mal
Minowa: mmal
consensus: pk

NRPSPredictor2 SVM: gly,ala
Stachelhaus code: gly
Minowa: leu
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 20. Type = nrps-t1pks. Location: 492645 - 545253 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 21 - Other

Gene cluster description

Gene Cluster 21. Type = other. Location: 564141 - 607482 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 22 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp) + (mal) + (pk) + (pk)
SETTUDRAFT_161582
PKS signature: mal
Minowa: mmal
consensus: pk

SETTUDRAFT_161586
PKS signature: mal
Minowa: mmal
consensus: pk

SETTUDRAFT_161587
PKS signature: mal
Minowa: mal
consensus: mal

SETTUDRAFT_28805
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: val
Minowa: pip
consensus: nrp

Gene cluster description

Gene Cluster 22. Type = t1pks. Location: 405520 - 524673 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 23 - Terpene

Gene cluster description

Gene Cluster 23. Type = terpene. Location: 130258 - 151652 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 24 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_185084
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 24. Type = t1pks. Location: 1 - 37122 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 25 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
SETTUDRAFT_40268
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 25. Type = t1pks. Location: 57574 - 105744 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 26 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp-nrp-nrp-nrp)
SETTUDRAFT_179280
NRPSPredictor2 SVM: hydrophilic
Stachelhaus code: orn
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: leu
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: tyr
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: pro
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 26. Type = nrps. Location: 395602 - 457804 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 27 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_171983
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 27. Type = t1pks. Location: 1668111 - 1716182 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 28 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
SETTUDRAFT_154973
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 28. Type = t1pks. Location: 3080977 - 3129360 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 29 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_21011
PKS signature: mal
Minowa: mxmal
consensus: pk

Gene cluster description

Gene Cluster 29. Type = t1pks. Location: 3432451 - 3479694 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 30 - T1pks-nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal) + (nrp)
SETTUDRAFT_92491
PKS signature: mal
Minowa: mal
consensus: mal

SETTUDRAFT_155102
NRPSPredictor2 SVM: N/A
Stachelhaus code: phe
Minowa: orn
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 30. Type = t1pks-nrps. Location: 306299 - 358493 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 31 - Terpene

Gene cluster description

Gene Cluster 31. Type = terpene. Location: 1769366 - 1790712 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 32 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_33341
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 32. Type = t1pks. Location: 2357943 - 2405329 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 33 - Other

Gene cluster description

Gene Cluster 33. Type = other. Location: 457824 - 500958 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 34 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_93994
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 34. Type = t1pks. Location: 1520110 - 1568361 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 35 - T2fas

Gene cluster description

Gene Cluster 35. Type = t2fas. Location: 1816403 - 1858032 nt. Click on genes for more information.
Show pHMM detection rules used
t2fas: (t2fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 36 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_22370
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 36. Type = t1pks. Location: 50512 - 98088 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 37 - T1fas

Gene cluster description

Gene Cluster 37. Type = t1fas. Location: 1809073 - 1854767 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 38 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(ala-nrp-nrp-nrp)
SETTUDRAFT_141443
NRPSPredictor2 SVM: N/A
Stachelhaus code: ala
Minowa: ala
consensus: ala

NRPSPredictor2 SVM: gly,ala,val,leu,ile,abu,iva
Stachelhaus code: pro
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: trp
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: hydrophilic
Stachelhaus code: gly
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 38. Type = nrps. Location: 2057032 - 2113337 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 39 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:

Gene cluster description

Gene Cluster 39. Type = t1pks. Location: 2223460 - 2267361 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 40 - Other

Gene cluster description

Gene Cluster 40. Type = other. Location: 461091 - 504939 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 41 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_181366
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 41. Type = t1pks. Location: 1382178 - 1429965 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 42 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp-ala)
SETTUDRAFT_97841
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: val
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: ala
Minowa: ala
consensus: ala

Database cross-links

Gene cluster description

Gene Cluster 42. Type = nrps. Location: 1899348 - 1944485 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 43 - Terpene

Gene cluster description

Gene Cluster 43. Type = terpene. Location: 12759 - 35614 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 44 - Terpene

Gene cluster description

Gene Cluster 44. Type = terpene. Location: 597965 - 619594 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 45 - Other

Gene cluster description

Gene Cluster 45. Type = other. Location: 987319 - 1030673 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 46 - T1fas-nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp-nrp-nrp-nrp-nrp) + (pk)
SETTUDRAFT_174337
PKS signature: N/A
Minowa: trans-1,2-CPDA
consensus: pk

SETTUDRAFT_99181
NRPSPredictor2 SVM: N/A
Stachelhaus code: pro
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: gly,ala,val,leu,ile,abu,iva
Stachelhaus code: ser
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: leu
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: cha
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: gly,ala,val,leu,ile,abu,iva
Stachelhaus code: arg
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 46. Type = t1fas-nrps. Location: 1622148 - 1689532 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 47 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_100517
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 47. Type = t1pks. Location: 142363 - 189917 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 48 - Other

Gene cluster description

Gene Cluster 48. Type = other. Location: 1302032 - 1345265 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 49 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_158064
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 49. Type = t1pks. Location: 1688392 - 1737224 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 50 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
SETTUDRAFT_174734
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 50. Type = t1pks. Location: 1805519 - 1854360 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters