Identified secondary metabolite clusters

Cluster Type From To
The following clusters are from record KB445791.1:
Cluster 1T1pks13652251412160
The following clusters are from record KB445793.1:
Cluster 2Terpene16184961639717
Cluster 3Other19936612037730
The following clusters are from record KB445794.1:
Cluster 4Terpene12909801312725
The following clusters are from record KB445795.1:
Cluster 5Nrps10377541085923
The following clusters are from record KB445796.1:
Cluster 6Ubia_cyclase900250941287
Cluster 7Other16468461691014
The following clusters are from record KB445798.1:
Cluster 8Ubia_cyclase493585550317
Cluster 9Ubia_cyclase568477622134
Cluster 10Ubia_cyclase864212916350
The following clusters are from record KB445800.1:
Cluster 11Terpene344398379194
Cluster 12Terpene420482441688
Cluster 13Other775595819699
Cluster 14Terpene832379853663
Cluster 15Other948033992135
Cluster 16T1pks13604771409480
The following clusters are from record KB445802.1:
Cluster 17Other826653871192
The following clusters are from record KB445804.1:
Cluster 18Terpene275624300842
Cluster 19T1fas345315398216
Cluster 20Terpene10105581038610
The following clusters are from record KB445806.1:
Cluster 21Terpene220811244306
The following clusters are from record KB445809.1:
Cluster 22Terpene251191272720
Cluster 23Terpene590116614047
The following clusters are from record KB445812.1:
Cluster 24Nrps-t1pks305048356915
Cluster 25Other354643398720

Cluster 1 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-mal)
CERSUDRAFT_128472
PKS signature: N/A
Minowa: trans-1,2-CPDA
consensus: pk

PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 1. Type = t1pks. Location: 1365225 - 1412160 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 2 - Terpene

Gene cluster description

Gene Cluster 2. Type = terpene. Location: 1618496 - 1639717 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 3 - Other

Gene cluster description

Gene Cluster 3. Type = other. Location: 1993661 - 2037730 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 4 - Terpene

Gene cluster description

Gene Cluster 4. Type = terpene. Location: 1290980 - 1312725 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 5 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp)
CERSUDRAFT_172109
NRPSPredictor2 SVM: N/A
Stachelhaus code: lys
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 5. Type = nrps. Location: 1037754 - 1085923 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 6 - Ubia_cyclase

Gene cluster description

Gene Cluster 6. Type = UbiA_cyclase. Location: 900250 - 941287 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 7 - Other

Gene cluster description

Gene Cluster 7. Type = other. Location: 1646846 - 1691014 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 8 - Ubia_cyclase

Gene cluster description

Gene Cluster 8. Type = UbiA_cyclase. Location: 493585 - 550317 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 9 - Ubia_cyclase

Gene cluster description

Gene Cluster 9. Type = UbiA_cyclase. Location: 568477 - 622134 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 10 - Ubia_cyclase

Gene cluster description

Gene Cluster 10. Type = UbiA_cyclase. Location: 864212 - 916350 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 11 - Terpene

Gene cluster description

Gene Cluster 11. Type = terpene. Location: 344398 - 379194 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 12 - Terpene

Gene cluster description

Gene Cluster 12. Type = terpene. Location: 420482 - 441688 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 13 - Other

Gene cluster description

Gene Cluster 13. Type = other. Location: 775595 - 819699 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 14 - Terpene

Gene cluster description

Gene Cluster 14. Type = terpene. Location: 832379 - 853663 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 15 - Other

Gene cluster description

Gene Cluster 15. Type = other. Location: 948033 - 992135 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 16 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
CERSUDRAFT_96782
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 16. Type = t1pks. Location: 1360477 - 1409480 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 17 - Other

Gene cluster description

Gene Cluster 17. Type = other. Location: 826653 - 871192 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 18 - Terpene

Gene cluster description

Gene Cluster 18. Type = terpene. Location: 275624 - 300842 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 19 - T1fas

Gene cluster description

Gene Cluster 19. Type = t1fas. Location: 345315 - 398216 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 20 - Terpene

Gene cluster description

Gene Cluster 20. Type = terpene. Location: 1010558 - 1038610 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 21 - Terpene

Gene cluster description

Gene Cluster 21. Type = terpene. Location: 220811 - 244306 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 22 - Terpene

Gene cluster description

Gene Cluster 22. Type = terpene. Location: 251191 - 272720 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 23 - Terpene

Gene cluster description

Gene Cluster 23. Type = terpene. Location: 590116 - 614047 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

No significant ClusterBlast hits found.

Cluster 24 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp) + (pk-nrp) + (pk-nrp)
CERSUDRAFT_144067
PKS signature: mal
Minowa: mmal
consensus: pk

NRPSPredictor2 SVM: hydrophobic-aromatic
Stachelhaus code: ser
Minowa: ala
consensus: nrp

CERSUDRA_1
PKS signature: mal
Minowa: mmal
consensus: pk

NRPSPredictor2 SVM: hydrophobic-aromatic
Stachelhaus code: ser
Minowa: ala
consensus: nrp

CERSUDRAFT_118967
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: N/A
Minowa: dhpg
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 24. Type = nrps-t1pks. Location: 305048 - 356915 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 25 - Other

Gene cluster description

Gene Cluster 25. Type = other. Location: 354643 - 398720 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters