Identified secondary metabolite clusters

Cluster Type From To
The following clusters are from record KI925455.1:
Cluster 1Terpene12003701221635
Cluster 2Terpene29826833003994
The following clusters are from record KI925456.1:
Cluster 3Terpene631319652411
Cluster 4Other28635002907244
The following clusters are from record KI925457.1:
Cluster 5Other431947476037
Cluster 6Terpene10412201073884
Cluster 7Terpene13334281354547
Cluster 8Siderophore16545381671014
Cluster 9T1fas24025002455171
The following clusters are from record KI925458.1:
Cluster 10T1pks-terpene257382321709
Cluster 11Terpene823648844837
The following clusters are from record KI925459.1:
Cluster 12Ubia_cyclase24044612452365
The following clusters are from record KI925460.1:
Cluster 13Terpene422500443772
Cluster 14Other762573807104
Cluster 15Other22563462300142
The following clusters are from record KI925461.1:
Cluster 16Terpene3481656502
The following clusters are from record KI925462.1:
Cluster 17Terpene12056431257696
The following clusters are from record KI925463.1:
Cluster 18T1pks387627438545
Cluster 19Other15639621608183
The following clusters are from record KI925464.1:
Cluster 20Other143258
Cluster 21Other99932145024
The following clusters are from record KI925465.1:
Cluster 22Other549219593744
Cluster 23Other13746181418845
Cluster 24Other14135441457759
Cluster 25Other14762611520498
The following clusters are from record KI925467.1:
Cluster 26Other768691812942

Cluster 1 - Terpene

Gene cluster description

Gene Cluster 1. Type = terpene. Location: 1200370 - 1221635 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 2 - Terpene

Gene cluster description

Gene Cluster 2. Type = terpene. Location: 2982683 - 3003994 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 3 - Terpene

Gene cluster description

Gene Cluster 3. Type = terpene. Location: 631319 - 652411 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 4 - Other

Gene cluster description

Gene Cluster 4. Type = other. Location: 2863500 - 2907244 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 5 - Other

Gene cluster description

Gene Cluster 5. Type = other. Location: 431947 - 476037 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 6 - Terpene

Gene cluster description

Gene Cluster 6. Type = terpene. Location: 1041220 - 1073884 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 7 - Terpene

Gene cluster description

Gene Cluster 7. Type = terpene. Location: 1333428 - 1354547 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 8 - Siderophore

Gene cluster description

Gene Cluster 8. Type = siderophore. Location: 1654538 - 1671014 nt. Click on genes for more information.
Show pHMM detection rules used
siderophore: (IucA_IucC)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 9 - T1fas

Gene cluster description

Gene Cluster 9. Type = t1fas. Location: 2402500 - 2455171 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 10 - T1pks-terpene

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal) + (mal)
HETIRDRAFT_316970
PKS signature: mal
Minowa: mal
consensus: mal

HETIRDRA_2
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 10. Type = t1pks-terpene. Location: 257382 - 321709 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 11 - Terpene

Gene cluster description

Gene Cluster 11. Type = terpene. Location: 823648 - 844837 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 12 - Ubia_cyclase

Gene cluster description

Gene Cluster 12. Type = UbiA_cyclase. Location: 2404461 - 2452365 nt. Click on genes for more information.
Show pHMM detection rules used
UbiA_cyclase: (UbiA_cyclase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 13 - Terpene

Gene cluster description

Gene Cluster 13. Type = terpene. Location: 422500 - 443772 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 14 - Other

Gene cluster description

Gene Cluster 14. Type = other. Location: 762573 - 807104 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 15 - Other

Gene cluster description

Gene Cluster 15. Type = other. Location: 2256346 - 2300142 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 16 - Terpene

Gene cluster description

Gene Cluster 16. Type = terpene. Location: 34816 - 56502 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 17 - Terpene

Gene cluster description

Gene Cluster 17. Type = terpene. Location: 1205643 - 1257696 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 18 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk) + (nrp)
HETIRDRAFT_174228
PKS signature: N/A
Minowa: trans-1,2-CPDA
consensus: pk

HETIRDRAFT_174227
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: N/A
Minowa: orn
consensus: nrp

Gene cluster description

Gene Cluster 18. Type = t1pks. Location: 387627 - 438545 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 19 - Other

Gene cluster description

Gene Cluster 19. Type = other. Location: 1563962 - 1608183 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 20 - Other

Gene cluster description

Gene Cluster 20. Type = other. Location: 1 - 43258 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 21 - Other

Gene cluster description

Gene Cluster 21. Type = other. Location: 99932 - 145024 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 22 - Other

Gene cluster description

Gene Cluster 22. Type = other. Location: 549219 - 593744 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 23 - Other

Gene cluster description

Gene Cluster 23. Type = other. Location: 1374618 - 1418845 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 24 - Other

Gene cluster description

Gene Cluster 24. Type = other. Location: 1413544 - 1457759 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 25 - Other

Gene cluster description

Gene Cluster 25. Type = other. Location: 1476261 - 1520498 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 26 - Other

Gene cluster description

Gene Cluster 26. Type = other. Location: 768691 - 812942 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters