Identified secondary metabolite clusters

Cluster Type From To
The following clusters are from record CP003009.1:
Cluster 1T1pks553582600374
Cluster 2Terpene672704693978
Cluster 3T1pks26815322729598
Cluster 4Nrps61385866193589
Cluster 5Nrps-t1pks65734866626075
Cluster 6Terpene78053087826762
Cluster 7T3pks81480328189584
Cluster 8T1pks87233608770632
Cluster 9T1pks999626510044471
The following clusters are from record CP003010.1:
Cluster 10Nrps118796184185
Cluster 11T1pks51469655192679
Cluster 12T1pks91742759222684
The following clusters are from record CP003011.1:
Cluster 13T1pks172869
Cluster 14T1pks93172140431
Cluster 15Other139367182851
Cluster 16Terpene16547821676459
Cluster 17T1pks36201813678195
Cluster 18T1pks40134214060920
Cluster 19Nrps44100394458866
The following clusters are from record CP003012.1:
Cluster 20Hglks-lantipeptide140385
Cluster 21T1pks3271280803
Cluster 22T2fas30850163126517
The following clusters are from record CP003013.1:
Cluster 23Other27847072828354
Cluster 24T1pks28497122896316
Cluster 25T1fas34352203480491

Cluster 1 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
THITE_2106274
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 1. Type = t1pks. Location: 553582 - 600374 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 2 - Terpene

Gene cluster description

Gene Cluster 2. Type = terpene. Location: 672704 - 693978 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 3 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
THITE_40673
PKS signature: mal
Minowa: mxmal
consensus: pk

Gene cluster description

Gene Cluster 3. Type = t1pks. Location: 2681532 - 2729598 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 4 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(ala-nrp-nrp)
THITE_62324
NRPSPredictor2 SVM: N/A
Stachelhaus code: ala
Minowa: ala
consensus: ala

NRPSPredictor2 SVM: gly,ala,val,leu,ile,abu,iva
Stachelhaus code: pro
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: gly
Minowa: ala
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 4. Type = nrps. Location: 6138586 - 6193589 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 5 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-nrp)
THITE_115563
PKS signature: mal
Minowa: mmal
consensus: pk

NRPSPredictor2 SVM: asp,asn,glu,gln,aad
Stachelhaus code: val
Minowa: glu
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 5. Type = nrps-t1pks. Location: 6573486 - 6626075 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 6 - Terpene

Gene cluster description

Gene Cluster 6. Type = terpene. Location: 7805308 - 7826762 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 7 - T3pks

Gene cluster description

Gene Cluster 7. Type = t3pks. Location: 8148032 - 8189584 nt. Click on genes for more information.
Show pHMM detection rules used
t3pks: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 8 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
THITE_123823
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 8. Type = t1pks. Location: 8723360 - 8770632 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 9 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
THITE_47532
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 9. Type = t1pks. Location: 9996265 - 10044471 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 10 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp-nrp-nrp-nrp-nrp)
THITE_112015
NRPSPredictor2 SVM: phe,trp,phg,tyr,bht
Stachelhaus code: bht
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: glu,gln
Stachelhaus code: orn
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: leu
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: tyr
Minowa: ala
consensus: nrp

NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: ala
Minowa: lys
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 10. Type = nrps. Location: 118796 - 184185 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 11 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
THITE_35447
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 11. Type = t1pks. Location: 5146965 - 5192679 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 12 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
THITE_2088794
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 12. Type = t1pks. Location: 9174275 - 9222684 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 13 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal) + (pk)
THITE_53646
PKS signature: mal
Minowa: mxmal
consensus: pk

THITE_125678
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 13. Type = t1pks. Location: 1 - 72869 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 14 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
THITE_132390
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 14. Type = t1pks. Location: 93172 - 140431 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 15 - Other

Gene cluster description

Gene Cluster 15. Type = other. Location: 139367 - 182851 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 16 - Terpene

Gene cluster description

Gene Cluster 16. Type = terpene. Location: 1654782 - 1676459 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or dmat or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 17 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk) + (nrp)
THITE_170170
PKS signature: mal
Minowa: mmal
consensus: pk

THITE_2155249
NRPSPredictor2 SVM: N/A
Stachelhaus code: N/A
Minowa: pip
consensus: nrp

Gene cluster description

Gene Cluster 17. Type = t1pks. Location: 3620181 - 3678195 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 18 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk)
THITE_2050301
PKS signature: mal
Minowa: mmal
consensus: pk

Gene cluster description

Gene Cluster 18. Type = t1pks. Location: 4013421 - 4060920 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 19 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp)
THITE_136279
NRPSPredictor2 SVM: hydrophobic-aliphatic
Stachelhaus code: ala
Minowa: aeo
consensus: nrp

Database cross-links

Gene cluster description

Gene Cluster 19. Type = nrps. Location: 4410039 - 4458866 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 20 - Hglks-lantipeptide

Gene cluster description

Gene Cluster 20. Type = hglks-lantipeptide. Location: 1 - 40385 nt. Click on genes for more information.
Show pHMM detection rules used
hglks: (hglE or hglD)
lantipeptide: ((Lant_dehyd_N & Lant_dehyd_C) or cluster(LANC_like,Flavoprotein) or cluster(LANC_like,Trp_halogenase) or cluster(LANC_like,p450) or (LANC_like & Pkinase) or (LANC_like & DUF4135) or cluster(LANC_like,Lant_dehyd_N) or cluster(LANC_like,Lant_dehyd_C) or cluster(LANC_like,adh_short) or cluster(LANC_like,adh_short_C2) or TIGR03731 or Antimicr18 or Gallidermin or L_biotic_A or TIGR03731 or leader_d or leader_eh or leader_abc or mature_d or mature_ab or mature_a or mature_b or mature_ha or mature_h_beta or lacticin_l or lacticin_mat or LD_lanti_pre or strep_PEQAXS)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

No core peptides found.

Homologous gene clusters

Cluster 21 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
THITE_2079455
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 21. Type = t1pks. Location: 32712 - 80803 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 22 - T2fas

Gene cluster description

Gene Cluster 22. Type = t2fas. Location: 3085016 - 3126517 nt. Click on genes for more information.
Show pHMM detection rules used
t2fas: (t2fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 23 - Other

Gene cluster description

Gene Cluster 23. Type = other. Location: 2784707 - 2828354 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Cluster 24 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(mal)
THITE_44861
PKS signature: mal
Minowa: mal
consensus: mal

Gene cluster description

Gene Cluster 24. Type = t1pks. Location: 2849712 - 2896316 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Cluster 25 - T1fas

Gene cluster description

Gene Cluster 25. Type = t1fas. Location: 3435220 - 3480491 nt. Click on genes for more information.
Show pHMM detection rules used
t1fas: (bt1fas or ft1fas)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters